BDBM384207 (1R)-8-[3-(2-amino- 3-chloropyridin-4- yl)-1H-pyrazolo[3,4- b]pyrazin-6-yl]-8- azaspiro[4.5]decan- 1-amine::US10280171, Example 130::US10851110, Example 130::US11466017, Example 130
SMILES N[C@@H]1CCCC11CCN(CC1)c1cnc2c(n[nH]c2n1)-c1ccnc(N)c1Cl
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384207
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 65nMAssay Description:KYSE-520 cells (10 k cells/well) were grown in 384-well plate in 20 uL of medium (RPMI-1640, without phenol red, containing 10% FBS) at 37° C. with 5...More data for this Ligand-Target Pair